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 Fruit flies found to “think” before they act

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Fruit flies found to “think” before they act Vide
PostSubject: Fruit flies found to “think” before they act   Fruit flies found to “think” before they act Icon_minitimeThu May 22, 2014 10:29 pm

Fruit flies “think” be­fore they act, a study sug­gests.

In ex­pe­ri­ments in which the in­sects had to tell apart ev­er more si­m­i­lar con­centra­t­ions of an odor, re­search­ers found that the flies don’t act in­stinc­tively or im­pul­sive­ly, but seem to ac­cu­mu­late in­forma­t­ion be­fore act­ing. That has been con­sid­ered a sign of high­er in­tel­li­gence.

“Fruit flies have a sur­pris­ing men­tal ca­pa­city,” said Uni­vers­ity of Ox­ford neu­ro­sci­ent­ist Gero Miesen­böck, in whose lab­o­r­a­to­ry the new re­search was per­formed. “Free­dom of ac­tion from au­to­mat­ic im­pulses is con­sid­ered a hall­mark of cog­ni­tion or in­tel­li­gence.”

The re­search­ers al­so found that a gene called FoxP, ac­tive in a small set of brain cells, facili­tates the choos­ing.

“Be­fore a de­ci­sion is made, brain cir­cuits col­lect in­forma­t­ion like a buck­et col­lects wa­ter. Once the ac­cu­mu­lated in­forma­t­ion has ris­en to a cer­tain lev­el, the de­ci­sion is trig­gered. When FoxP is de­fec­tive, ei­ther the flow of in­forma­t­ion in­to the buck­et is re­duced to a trick­le, or the buck­et has sprung a leak,” said Ox­ford’s Shamik Das­Gupta, the lead au­thor of the stu­dy.

The re­search­ers watched Dro­soph­i­la fruit flies choose be­tween two con­centra­t­ions of an odor pre­sented to them from op­po­site ends of a nar­row cham­ber, hav­ing been trained to avoid one con­centra­t­ion. When the con­centra­t­ions were very dif­fer­ent and easy to tell apart, the flies usu­ally de­cid­ed quickly and went to the cor­rect end of the cham­ber. When the con­centra­t­ions were very close and hard to tell apart, the flies took much long­er to de­cide and made more mis­takes.

The re­search­ers found that math­e­mat­i­cal mod­els de­vel­oped to de­scribe the mech­a­nisms of de­ci­sion mak­ing in hu­mans and pri­ma­tes al­so matched the fruit fly be­hav­ior. And flies with muta­t­ions in the FoxP gene were par­tic­u­larly in­de­ci­sive. The re­search­ers tracked down the gene’s ac­ti­vity to a small clus­ter of around 200 neu­rons, or brain cells, out of the 200,000 in the fruit fly brain, im­pli­cat­ing these neu­rons in the evidence-gathering pro­cess.

The team re­ports its find­ings in the jour­nal Sci­ence.

Fruit flies have one FoxP gene, while hu­mans have four re­lat­ed FoxP genes. Hu­man FoxP1 and FoxP2 have pre­vi­ously been as­so­ci­at­ed with lan­guage and cog­ni­tive de­vel­op­ment. The genes have al­so been linked to the abil­ity to learn fi­ne move­ment se­quences, such as play­ing the pia­no.

“We don’t know why this gene pops up in such di­verse men­tal pro­cesses as lan­guage, de­ci­sion-mak­ing and mo­tor learn­ing,” said Miesen­böck. But “one fea­ture com­mon to all of these pro­cesses is that they un­fold over time.”

“FoxP is not a ‘lan­guage gene,’ a ‘de­ci­sion-mak­ing gene,’” or any more spe­cif­ic cat­e­go­ry, he added. “What FoxP does give us is a tool to un­der­stand the brain cir­cuits in­volved in these pro­cesses. It has al­ready led us to a site in the brain that is im­por­tant in de­ci­sion-mak­ing.”

http://www.world-science.net/othernews/140522_decision.htm
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