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 Online gamers crack AIDS enzyme puzzle

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RR Phantom

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Online gamers crack AIDS enzyme puzzle Vide
PostSubject: Online gamers crack AIDS enzyme puzzle   Online gamers crack AIDS enzyme puzzle Icon_minitimeMon Sep 19, 2011 4:46 am
Online gamers have achieved a feat beyond the realm of Second Life or Dungeons and Dragons: they have deciphered the structure of an enzyme of an AIDS-like virus that had thwarted scientists for a decade.

The exploit was published on Sunday in the journal Nature Structural & Molecular Biology, where - exceptionally in scientific publishing - both gamers and researchers are honoured as co-authors.

Online gamers crack AIDS enzyme puzzle Art_competition-420x0

Their target was a monomeric protease enzyme, a cutting agent in the complex molecular tailoring of retroviruses, a family that includes HIV.

Figuring out the structure of proteins is vital for understanding the causes of many diseases and developing drugs to block them.

But a microscope gives only a flat image of what to the outsider looks like a plate of one-dimensional scrunched-up spaghetti. Pharmacologists, though, need a 3D picture that "unfolds" the molecule and rotates it in order to reveal potential targets for drugs.

http://www.smh.com.au/digital-life/games/online-gamers-crack-aids-enzyme-puzzle-20110919-1kgq2.html
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